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吃“蛋糕”好似“嗑药”吗?古朵新闻√
发布时间:2019-10-15   点击次数:118次

对一些人来说,巧克力蛋糕可能会引发一种与“非法药物”相当的快乐。宾夕法尼亚大学生物学家提供了对这一联xi的新见解,揭示了大脑对食物和药物等奖励的不同反应。
在本周发表在《Neuron》杂志的这项研究,由助理教授J.Nicholas Betley、博士后研究员Amber L.Alhadeff和文理学院的研究生Nitsan Goldstein领导,研究表明,在小鼠身上,吃东西会降低神经元活动,这些神经元原本通过不同于酒精和药物的途径向大脑发出饥饿信号,而酒精和药物同样可以抑制食欲。这项研究也揭示了引起愉快的多巴胺释放回路与饥饿神经元的活动有关,这表明药物和酒精不仅可以劫持大脑的奖赏回路,而且还可以劫持那些负责发出饥饿信号的回路,强化服务“上瘾”的行为。

“JIANGLIXINHAO,BUGUANSHISHIWUHAISHIYAOWU,TONGGUOBUTONGDETUJINGJINRUDANAO,”ZHEIXIANGGONGZUODETONGXUNZUOZHEBetleySHUO。“YIDANTAMENJINRUDANAO,TAMENJIUHUIZAIXIAQIUNAOJIESHENJINGYUANHEJIANGSHANGSHENJINGYUANZHIJIANXINGCHENGYIGEXIANGHULIANJIEDEWANGLUO。ZHEIKENENGSHIYINWEIYAOWUBUJINTONGGUOZENGJIADUOBAANDEFENGZHIERDEDAOJIAQIANG,ERQIEHAINENGTONGGUOJIANSHAOSHINIGANDAOJUSANGDEJIESHENJINGYUANDEHUODONGERDEDAOJIAQIANG。”

SUIZHEDUIZHEIXIETUJINGDEJINYIBULEJIE,YANJIURENYUANSHUO,TAMENDEFAXIANKENENGHUIWEIYANZHIGENGYOUXIAODEJIANfeiYAOSHENZHICHENGYINLIAOFATIGONGYIJU。

 

海南七星彩BetleyJIQITONGSHIDEYANJIUBIAOMING,ZAIXIAOSHUTINEIZHURURENHEYIZHONGHONGLIANGYINGYANGSU(RENHEHANKALULIDESHIWU),DOUHUIYIZHIAgRPSHENJINGYUANDEHUODONG,ERAgRPSHENJINGYUANDEHUODONGHUIDAOZHIYUJIEYOUGUANDEBUYUKUAIDEGANJUE。WEIGAOSUDANAO“TAYIJINGDANJINLIANGJUELE”DEXINHAOYANZHEMIZOUSHENJINGCHUANDI。


海南七星彩研究人员对酒精是否也能引起同样的效果感到好奇,他们发现即使在迷走神经通路被破坏的情况下,酒精也能在小鼠身上引起同样的效果。

海南七星彩AlhadeffSHUO:“RUGUOWOMENQIEDUANZHEITIAOLU,GAORELIANG、GAOHUIBAODESHIWUJIUBUNENGZAIXIANGJIESHENJINGYUANFACHUZHEIZHONGXINHAO,SUIRANJIUJINGHAIKEYI。”

海南七星彩JIEXIALAI,YANJIUXIAOZUSHITUYONGKEkaYIN、NIGUDINGHEanFEITAMINGZUOTONGYANGDESHIYAN,ZHEIXIEYAOWUYIJINGBEIZHENGMINGJUYOUYIZHISHIYUDEHUOXING,DEDAOLEXIANGTONGJIEGUO。YANJIUXIAOZUSHUO,WOMENFAXIANFEIYINGYANGWUZHINENGGOUCHIXUDIAOJIEAgRPSHENJINGYUAN。

海南七星彩“LINGRENXINGFENDESHI,YANJIUJIEGUOBIAOMING,RUGUOYOURENZAIJIANfeiKONGZHIYINSHI,YOUYIXIEYAOLIJIZHIKEYIYONGLAIJIANSHAOZHEIXIESHENJINGYUANDEHUODONGDEHUA,JIUNENGJIANQINGJIEGAN,”AlhadeffSHUO。

YOUYUZHIDAOJIUJINGHEYAOWUYEHUICHUFADUOBAANDESHIFANG(DUOBAANSHIYIZHONGYU“JIANGSHANG”GANYOUGUANDESHENJINGDIZHI,YEYUCHENGYINYOUGUAN),YANJIUXIAOZUGUANCHADAODUOBAANSHENJINGYUANDEHUODONGSUIAgRPSHENJINGYUANDEHUODONGJIANSHAOTONGSHIZENGJIA。

YANJIURENYUANLIYONGYIZHONGJISHUZAIBUBODUODONGWUSHIWUDEQINGKUANGXIAJIHUOAgRPSHENJINGYUAN,YANJIUZHEIXIEJIESHENJINGYUANRUHEYINGXIANGDUOBAANXINHAO。ZAIMEIYOUSHIWUJIANGLIDEQINGKUANGXIA,TAMENFAXIANDUOBAANSHENJINGYUANDUIAgRPSHENJINGYUANDEJIHUOFANYINGHENXIAO。DANSHI,DANGYIZHIAgRPBEIJIHUODEDONGWUBEIWEISHISHI,DUOBAANDEJIZENGSHENZHIBIZHENGCHANGQINGKUANGXIAHAIYAOGAO。HUANJUHUASHUO,DANGDONGWUJIESHI,AgRPSHENJINGYUANSHISHIWUXIANDEGENGYOU“HUIBAO”。

GoldsteinSHUO:“WOMENHENJINGYADIFAXIANZHEIXIEAgRPSHENJINGYUANSIHUZAIXIANGDUOBAANSHENJINGYUANFASONGXINHAO,DANZAIDONGWUDEDAOJIANGLIZHIQIAN,WOMENWUFAJIANCEDAOZHEIYIDIAN。ZHEIBIAOMING,YIGEJIANJIEDEHUODIAOJIEXINGDEHUILUJIEDAOJIEHEDANAOZHONGJIANGSHANGSHENJINGYUANZHIJIANDEXIANGHUZUOYONG。”

TONGYANGDESHIQINGYEFASHENGZAIDONGWUFUYONGNIGUDINGDENGYAOWUSHI。

JIEXIALAI,YANJIUXIAOZUHAIYANJIULEJIUJINGHEYAOWUDEJIANGLIXINHAOYUSHIWUZHIJIANDECHAYI,BINGJIEKAITAMENJIESHIDEDUOBAANSHENJINGYUANHEAgRPSHENJINGYUANZHIJIANDELIANxi。LIYONGXIANJINDEXINJISHU,TAMENJIANGJIANCHADANGESHENJINGYUAN,KANKANTAMENSUOGUANCHADAODEYINGXIANGSHIFOUSHIYOUYUDANAOZHONGSHENJINGYUANDEXIAOYAQUNHUODONGYINQI。

BetleySHUO,RUGUOTAMENNENGGOUCHENGGONGDIZHAODAOYIZHONGXINDE、KETONGGUOYAOWUZHILIAODETUJINGLAIZHILIAOZHEIXIELIANJIEDESHENJINGHUILU,JIANGHUIHENSHOUHUANYING,YINWEIMUQIANXUDUOJIANfeiYAOWUDOUYOUBUYUKUAIDEFUZUOYONG,BIRUeXINDENG。

TASHUO:“DANGRENMENGANJUEBUSHUFU,JIUHENNANJIANCHIFUYONGZHEIXIEYAOWU。WOMENDEYANJIUJIEGUOBIAOMING,JINRUDANAODEFANGSHIDUOZHONGDUOYANG,YEXUTONGGUOJIEHEQITACELVE,WOMENKEYIKEFUZHEIXIEWENTI。”

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